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Neonatal Medicine

Hyperbilirubinemia Management


Randomised controlled trial of single phototherapy with reflecting curtains versus double phototherapy in term newborns with hyperbilirubinaemia. (opens new window)

Abd Hamid IJ, M Iyen MI, Ibrahim NR, Abd Majid N, Ramli N, Van Rostenberghe H.

Source‎: J Paediatr Child Health 2013;49(5):375-9.

Indexed‎: PubMed 23573836

DOI‎: 10.1111/jpc.12192 (opens new window)

Phototherapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. (opens new window)

Bhutani VK; Committee on Fetus and Newborn; American Academy of Pediatrics.

Source‎: Pediatrics 2011;128(4):e1046-52.

Indexed‎: PubMed 21949150

DOI‎: 10.1542/peds.2011-1494 (opens new window)

High-intensity phototherapy for the treatment of severe nonhaemolytic neonatal hyperbilirubinemia. (opens new window)

de Carvalho M, Mochdece CC, Sá CA, Moreira ME.

Source‎: Acta Paediatr 2011;100(4):620-3.

Indexed‎: PubMed 21251060

DOI‎: 10.1111/j.1651-2227.2011.02170.x (opens new window)

Efficacy of phototherapy for neonatal jaundice is increased by the use of low-cost white reflecting curtains. (opens new window)

Djokomuljanto S, Quah BS, Surini Y, Noraida R, Ismail NZ, Hansen TW, Van Rostenberghe H.

Source‎: Arch Dis Child Fetal Neonatal Ed 2006;91(6):F439-42.

Indexed‎: PubMed 16877479

DOI‎: 10.1136/adc.2006.095687 (opens new window)

Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia. (opens new window)

Gholitabar M, McGuire H, Rennie J, Manning D, Lai R.

Source‎: Cochrane Database Syst Rev 2012;(12):CD009017.

Indexed‎: PubMed 23235669

DOI‎: 10.1002/14651858.CD009017.pub2 (opens new window)

Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates. (opens new window)

Kumar P, Chawla D, Deorari A.

Source‎: Cochrane Database Syst Rev 2011;(12):CD007969.

Indexed‎: PubMed 22161417

DOI‎: 10.1002/14651858.CD007969.pub2 (opens new window)

Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study. (opens new window)

Morris BH, Tyson JE, Stevenson DK, Oh W, Phelps DL, O'Shea TM, McDavid GE, Van Meurs KP, Vohr BR, Grisby C, Yao Q, Kandefer S, Wallace D, Higgins RD.

Source‎: J Perinatol 2013;33(2):126-33.

Indexed‎: PubMed 22499082

DOI‎: 10.1038/jp.2012.39 (opens new window)

Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants. (opens new window)

Okwundu CI, Okoromah CA, Shah PS.

Source‎: Cochrane Database Syst Rev 2012;(1):CD007966.

Indexed‎: PubMed 22258977

DOI‎: 10.1002/14651858.CD007966.pub2 (opens new window)

The effect of clofibrate with phototherapy in late pre-term newborns with non-hemolytic jaundice. (opens new window)

Sakha SH, Gharehbaghi MM, Rahbani ME.

Source‎: Indian J Med Sci 2009;63(5):174-9.

Indexed‎: PubMed 19584487

DOI‎: 10.4103/0019-5359.53162 (opens new window)

A randomized trial of phototherapy with filtered sunlight in African neonates. (opens new window)

Slusher TM, Olusanya BO, Vreman HJ, Brearley AM, Vaucher YE, Lund TC, Wong RJ, Emokpae AA, Stevenson DK.

Source‎: N Engl J Med 2015;373(12):1115-24.

Indexed‎: PubMed 26376136

DOI‎: 10.1056/NEJMoa1501074 (opens new window)

Dose-response relationship of phototherapy for hyperbilirubinemia. (opens new window)

Vandborg PK, Hansen BM, Greisen G, Ebbesen F.

Source‎: Pediatrics 2012;130(2):e352-7.

Indexed‎: PubMed 22802603

DOI‎: 10.1542/peds.2011-3235 (opens new window)

Intravenous Immunoglobulin

High-dose intravenous immunoglobulin therapy in neonatal immune haemolytic jaundice. (opens new window)

Alpay F, Sarici SU, Okutan V, Erdem G, Ozcan O, Gökçay E.

Source‎: Acta Paediatr 1999;88(2):216-9.

Indexed‎: PubMed 10102158 (opens new window)

High-dose intravenous immunoglobulin therapy for rhesus haemolytic disease. (opens new window)

Dağoğlu T, Ovali F, Samanci N, Bengisu E.

Source‎: J Int Med Res 1995;23(4):264-71.

Indexed‎: PubMed 7589769

DOI‎: 10.1177/030006059502300406 (opens new window)

Intravenous immune globulin reduces the need for exchange transfusions in Rhesus and ABO incompatibility. (opens new window)

Huizing K, Røislien J, Hansen T.

Source‎: Acta Paediatr 2008;97(10):1362-5.

Indexed‎: PubMed 18616629

DOI‎: 10.1111/j.1651-2227.2008.00915.x (opens new window)

Intravenous immunoglobulin G (IVIG) therapy for significant hyperbilirubinemia in ABO hemolytic disease of the newborn. (opens new window)

Miqdad AM, Abdelbasit OB, Shaheed MM, Seidahmed MZ, Abomelha AM, Arcala OP.

Source‎: J Matern Fetal Neonatal Med 2004;16(3):163-6.

Indexed‎: PubMed 15590442

DOI‎: 10.1080/14767050400009873 (opens new window)

Tin Mesoporphyrin

Clinical trial of tin mesoporphyrin to prevent neonatal hyperbilirubinemia. (opens new window)

Bhutani VK, Poland R, Meloy LD, Hegyi T, Fanaroff AA, Maisels MJ.

Source‎: J Perinatol 2016;36(7):533-9.

Indexed‎: PubMed 26938918

DOI‎: 10.1038/jp.2016.22 (opens new window)

Tin-mesoporphyrin in the treatment of severe hyperbilirubinemia in a very-low-birth-weight infant. (opens new window)

Reddy P, Najundaswamy S, Mehta R, Petrova A, Hegyi T.

Source‎: J Perinatol 2003;23(6):507-8.

Indexed‎: PubMed 13679941

DOI‎: 10.1038/ (opens new window)

Other Agents

Effect of ursodeoxycholic acid on indirect hyperbilirubinemia in neonates treated with phototherapy. (opens new window)

Honar N, Ghashghaei Saadi E, Saki F, Pishva N, Shakibazad N, Hosseini Teshnizi S.

Source‎: J Pediatr Gastroenterol Nutr 2016;62(1):97-100.

Indexed‎: PubMed 26020375

DOI‎: 10.1097/MPG.0000000000000874 (opens new window)

Hyperbilirubinemia in the newborn infant > or =35 weeks' gestation: an update with clarifications. (opens new window)

Maisels MJ, Bhutani VK, Bogen D, Newman TB, Stark AR, Watchko JF.

Source‎: Pediatrics 2009;124(4):1193-8.

Indexed‎: PubMed 19786452

DOI‎: 10.1542/peds.2009-0329 (opens new window)

A randomized controlled trial of fluid supplementation in term neonates with severe hyperbilirubinemia. (opens new window)

Mehta S, Kumar P, Narang A.

Source‎: J Pediatr 2005;147(6):781-5.

Indexed‎: PubMed 16356431

DOI‎: 10.1016/j.jpeds.2005.07.026 (opens new window)

Treatment of clofibrate in jaundiced low birth weight neonates. [English, Turkish abstract] (opens new window)

Mohammadzadeh A, Farhat AS, Amiri R, Esmaely H, Bagheri S.

Source‎: UHOD-Uluslar Hematol Onkol De (Int J Hematol Oncol) 2009;19(2):100-5.

Indexed‎: EMBASE 2009472903 (opens new window)

Efficacy of clofibrate on severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency (a randomized clinical trial). (opens new window)

Zahedpasha Y, Ahmadpour-Kacho M, Hajiahmadi M, Naderi S, Kamali AA.

Source‎: Southeast Asian J Trop Med Public Health 2008;39(3):557-61.

Indexed‎: PubMed 18564698 (opens new window)